An Exploratory Study of Sevoflurane as an Alternative for Difficult Sedation in Critically Ill Children. (Lima)

Mencía S, Palacios A, García M, et al. An Exploratory Study of Sevoflurane as an Alternative for Difficult Sedation in Critically Ill Children. Pediatr Crit Care Med. 2018 Mar 19. [Epub ahead of print]

OBJECTIVES: To analyze the effectiveness of inhaled sevoflurane in critically ill children with challenging sedation.

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Furosemide Response Predicts Acute Kidney Injury After Cardiac Surgery in Infants and Neonates. (Lima)

Borasino S, Wall KM, Crawford JH, et al. Furosemide Response Predicts Acute Kidney Injury After Cardiac Surgery in Infants and Neonates. Pediatr Crit Care Med. 2018 Apr;19(4):310-317.

OBJECTIVE: Cardiac surgery-induced acute kidney injury occurs frequently in neonates and infants and is associated with postoperative morbidity/mortality; early identification of cardiac surgery-induced acute kidney injury may be crucial to mitigate postoperative morbidity. We sought to determine if hourly or 6-hour cumulative urine output after furosemide in the first 24 hours after cardiopulmonary bypass could predict development of cardiac surgery-induced acute kidney injury and other deleterious outcomes.

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A Systematic Review of Risk Factors Associated With Cognitive Impairment After Pediatric Critical Illness. (Land)

Kachmar AG, et al. A Systematic Review of Risk Factors Associated With Cognitive Impairment After Pediatric Critical Illness. Pediatr Crit Care Med. 2018 Mar;19(3):e164-e171.

OBJECTIVES: To identify risk factors associated with cognitive impairment as assessed by neuropsychologic tests in neurotypical children after critical illness.

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RBC Transfusions Are Associated With Prolonged Mechanical Ventilation in Pediatric Acute Respiratory Distress Syndrome. (Land)

Zubrow ME, et al. RBC Transfusions Are Associated With Prolonged Mechanical Ventilation in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2018 Feb;19(2):e88-e96.

OBJECTIVES: Blood products are often transfused in critically ill children, although recent studies have recognized their potential for harm. Translatability to pediatric acute respiratory distress syndrome is unknown given that hypoxemia has excluded pediatric acute respiratory distress syndrome patients from clinical trials. We aimed to determine whether an association exists between blood product transfusion and survival or duration of ventilation in pediatric acute respiratory distress syndrome.

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